Search on ZonMw
Search on the website
Filters
40
results found for 'Antibiotic resistance'.
- Methicillin-resistant Staphylococcus aureus (MRSA) is characterised by clonal spread. MRSA clones are unequally distributed across the world and different clones are dominant at different times. AimThe MACOTRA project studied the interaction between MRSA, humans and the environment. The researchers used mathematical models to gain a better understanding of MRSA dynamics.ResultsA main predictor of…
- Bacteria can become resistant against beta-lactam antibiotics (Penicillin) by replacing their 3-4 peptide crosslinks by 3-3 crosslinks in the peptidoglycan layer in their cell wall that gives the bacterium its shape and protects it against mechanical stress. Peptidolglycan consists of a network of sugars strands that are interconnected by peptide crossbridges. Hardly anything was known about the…
- Respiratory tract infections are common and are increasingly caused by bacteria that are no longer sensitive to commonly used antibiotics.ObjectiveThis project aimed to expand the therapeutic arsenal against respiratory tract infections by testing agents that stimulate the immune system.ResultsThe AMC had 2 specific tasks. First, a culture system of human respiratory epithelial cells was set up…
