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… New intervention strategy for tuberculosis: blocking multiple essential targets Antibiotics Wed, 04/01/2015 - 12:00 - Thu, 11/01/2018 - 12:00 205400003 Project description … responsible for almost 1.5 million deaths per year. In recent years, different classes of drug resistant strains have emerged, making the discovery of novel tuberculostatic drugs a major … TB compounds is that they target a single molecule, which significantly increases the chance of resistance development.  Aim In this project, we have focused on type VII secretion (T7S) …

… and international levels by finding concrete solutions for zoonotic outbreaks and antimicrobial resistance, for instance. We are currently working on research into the prevention of infectious … a global health problem, as bacteria, viruses, parasites and fungi are increasingly becoming resistant to antibiotics, making the treatment of infectious diseases more difficult. Read more about the …

… and transmission Dr J.C.M (Janneke) Heijne, Stichting Amsterdam UMC What is the reason that antibiotics are slowly losing their effectiveness? In this project we are going to investigate … gonorrhoea, a sexually transmitted infection and one of very few pathogens for which strains resistant to all available antibiotics were described. We will make mathematical models of the development of resistance to antibiotics, based on laboratory experiments and data collected at sexual health …

… says Arfan: ‘There is a raft of substantive issues, such as obesity, pandemic preparedness, antibiotic resistance and ethical issues around new technologies. These matters require …

… will be studied to gain an understanding of risk factors and the effectiveness of current antibiotics policy in preventing new infections. View the project . Hide and Tick: One Health … aspergillosis (PA) are severe fungal infections that occur mainly in people with reduced resistance and chronic lung disease. There is currently no surveillance system for these … around the world. Some imported cases have been recorded in the Netherlands. C. auris is often resistant to antifungals, which makes it difficult to treat infections in patients. The lack of …

… contaminated, which could be seen from the presence of the many genes that render bacteria resistant to antibiotics. Particles in these dirty environments had more resistance genes than particles collected at clean locations. Also, particles to which …

… contaminated, which could be seen from the presence of the many genes that render bacteria resistant to antibiotics. Particles in these dirty environments had more resistance genes than particles collected at clean locations. Also, particles to which …

… Crosstalk between innate lymphocytes and the neuroepithelial unit as a driver of steroid-resistant asthma Prof. R. Gosens, University of Groningen Prof. R.W. Hendriks, Erasmus Medical … Haas, University Medical Center Utrecht Prof. S.J.J. Brouns, TU-Delft Bacterial antimicrobial resistance is an emerging health threat severely limiting treatment options for bacterial … for many different phages. Phage infection can also have an effect on bacterial virulence and antibiotic susceptibility. In this project we will study the role of defense and counter-defense …

… and economic costs. Furthermore, these treatments are rapidly becoming ineffective due to antibiotic resistance. MycoLipid will address this global challenge by developing novel host-directed therapies (HDTs), that are less susceptible to antibiotic resistance and can improve the safety and efficacy of existing drugs. These HDTs will …

… Also, the hygienic conditions make a difference with respect to the encountered number of resistance genes: the genes that bacteria exchange to strengthen their resistance to antibiotics. The response of the human immune system to the microbes present on microplastics …