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… the 'Ziektelastmeter' of Chronic Conditions, with modules for, amongst others, type 2 diabetes, heart failure and asthma. The 'Ziektelastmeter' tool has a positive effect on perceived quality … and fragmentation of care can be addressed. There currently are modules for COPD, asthma, heart failure and type 2 diabetes. The development of modules for osteoarthritis and …

… the treatment for patients with chronic kidney disease. To reduce their risks for kidney failure requiring dialysis and cardiovascular diseases, medications are required, but their … inhibitors (ICI) are effective cancer drugs. Unfortunately, they can cause inflammation of the heart, myocarditis. Currently, there is no strategy for identifying patients at risk and … heart is a severe cardiac muscle disease, often caused by a genetic mutation, and can lead to heart failure and death. Relatives of these patients also have an increased risk of developing …

… The programme will focus particularly on a number of specific groups of diagnoses: diabetes, heart failure, cardiovascular risk management, COPD, psychological disorders and musculoskeletal …

… of women, gender-diverse individuals, and people from various ethnic and cultural backgrounds. Heart failure is a clear example, because it presents differently in men and women. ZonMw feels …

… in clinical practice. The goal is to individualise treatment and reduce side-effects.        ThyHeart: man-vrouw verschillen in hart-en vaatziekten verklaard  door schildklierhomoon … begrijpen.       This proposal aims to investigate the link between chronic kidney disease and heart failure with preserved ejection fraction (HFpEF), a major subtype of heart failure affecting millions worldwide. Using state-of-the-art imaging technologies, such as …

… from treatment to prevention Every infection can lead to sepsis, a life-threatening organ failure caused by a dysregulated immune system response to invading bacteria and viruses. … be shifted from treatment to prevention. Prof. Niels P. Riksen, Radboudumc Preventing recurrent heart attacks Of all people that suffer a heart attack, approximately ten percent will have another heart attack or stroke within the next …

… for growing food crops that are less dependent on synthetic pesticides. Prevention of heart muscle degradation R.G.C. Maas, MSc  -> UMC Utrecht -> England  -> Nottingham Biodiscovery Institute  -> 24 months When heart muscle cells fail, there is no way back. The researcher will investigate common patterns … therapies will be tested to improve or even prevent heart muscle degradation in patients with heart failure. Getting a picture of redox-related cell states Dr. A. Sigaeva  -> University of …

… no funds and no plan.’ Under the leadership of Eduard, ZonMw initiated the project “System failures” in 2013 to find out more about the causes, consequences and solutions for system failures (problems in the research system). ‘We visited organisations, experts and deans and … However, Eduard does not want to disappear from view entirely. ‘This subject is close to my heart, and so I would like to remain in touch with developments.’ Eduard is pleased that he can …

… day in internal medicine, my first patient was Iris, a 90 year old lady with mild dementia and heart failure. The family all sat by her bedside, holding her hand and telling stories about …