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… malaise). What exactly happens in the skeletal muscles and blood, and what role does the immune system play in this? Researcher Rob Wüst of Vrije Universiteit Amsterdam aims to find … ‘Besides the changes in the skeletal muscles and blood, we also expect to find a disrupted immune system in people with ME/CFS. Our colleagues in South Africa have found that the …

… Converging neurobiological and immune pathways in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and … fatigue syndromes (PIFS) ME/CFS Chronic diseases FAIR data Neurology Fatigue Disrupted immune system Wed, 11/01/2023 - 12:00 - Mon, 11/01/2027 - 12:00 10091012110018 Patients with … Converging neurobiological and immune pathways in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and …

… have asymptomatic or mild disease. HYPOTHESIS Rare variants in genes associated with the immune system predispose children to develop MIS-C or post-COVID condition after infection with … workpackage we have two objectives: WP1.1. To diagnose previously unsuspected inborn error of immunity in cases of MIS-C or post-COVID condition. This approach enables the detection of … Genetic Risk factors for Multi-system Inflammatory Syndrome in Children and Pediatric Long COVID (GRIP) …

… on osteogenesis, rare diseases, schizophrenia, osteoarthritis, microbial fermentation and systemic sclerosis now receive funding to further develop their animal-free method. Human … and testing new drugs for systemic sclerosis by mimicking the disease using skin cells, immune cells and blood vessel cells in the lab.  Aan Animal-free Talent development and …

… by an artificial-intellingence ENhanced Surveillance program FUNGISENS Infectious disease Immune system Artificial Intelligence FAIR data Lung disease Wed, 05/01/2024 - 12:00 - Sat, 05/01/2027 … method By applying new software using artificial intelligence (AI), hospital information systems can be searched efficiently and anonymously.   This project investigates if such a …

… of children is susceptible to MIS-C or Long COVID. Genetic variants In the case of MIS-C, the immune system seems to be deregulated. We think that in these children, changes occur in genes that are important for a proper functioning of the immune system. Our question was whether these children might have a congenital immune disorder. …

… exposure is chronic. Inflammatory responses In the blood, the macrophages (a certain type of immune cell that normally engulfs pathogens) become extra active in response to microplastics. … inflammatory proteins, for example. In addition, certain immune cells from the adaptive immune system are extra active in response to polystyrene. Researchers noticed that ‘weathered’ …

… exposure is chronic. Inflammatory responses In the blood, the macrophages (a certain type of immune cell that normally engulfs pathogens) become extra active in response to microplastics. … inflammatory proteins, for example. In addition, certain immune cells from the adaptive immune system are extra active in response to polystyrene. Researchers noticed that ‘weathered’ …

… causes and unclear disease mechanisms. This project uses new technology to map ME/CFS patients' immune responses against hundreds of thousands of bacterial and viral structures. By comparing patients with healthy individuals, important differences in immune responses can be identified.  If certain viruses or bacteria turn out to be involved in … in the development of ME/CFS, such as the body's defences against infectious diseases (the immune system) and changes in the gut microbiome. It is still unknown how the interplay between …

… that have been made possible via ZonMw concern: Vaccination of people with a compromised immune system; Vaccination of adults and children with long COVID; Research into thrombosis and … vaccination, this concerns a booster vaccination. Vaccination of people with a compromised immune system At the initiative of ZonMw, 8 studies into the effect of Covid 19 vaccination in …

… the energy for daily activities. We think that the cause lies in abnormal behaviour in the immune system and the metabolism. But we won’t know for sure until we have enough patients for blood …

… with her research into the disease ME/CVS Blog 4: Customised treatment for ME/CFS using immune signatures Immunologist Wim Dik investigates whether an immune signature, the pattern of a dysregulated immune system, can be mapped so that effective treatment can be developed for ME/CVS. Blog 5: …