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… committees at ZonMw, including those for Q fever, Lyme’s disease and now also for ME/CFS.’ The immune system as a subject for enquiry Sjaak sees chairing the ME/CFS programme committee as a … blood to establish a diagnosis. However, there is more and more evidence of impairments to the immune system. So I want to encourage the sharing of data between programmes. Suppose there is a study within the post-COVID programme that demonstrates that a particular component of the immune system reacts intensively and causes fatigue, then it would be interesting to derive a …

… that live on the skin), or the skin’s defence mechanism. The skin itself is part of the immune system and also contains immune cells that destroy harmful bacteria. Researchers at the … are also underway examining how the effectiveness of treatments such as light therapy and systemic therapy weighs up against the cost and effort involved (efficiency). ZonMw funds …

… (AutonoME) EnergiseME: EvaluatioN of thE link between auto-immunity and deRanGements in Immune cell metaboliSm and function in ME/CFS Converging neurobiological and immune pathways in … and post-infectious fatigue syndromes (PIFS) Brain changes in ME/CFS: Focus on the stress and immune system Explaining skeletal muscle-related symptoms in patients with ME/CFS: from skeletal …

… by invasion of DNA from other microorganisms, bacteriophages or plasmids. The adaptive immune system (CRISPR-Cas) protects DNA from this threat. By linking spacers to the source, we … 25-40% of whom succumb to the disease. Survivors often have chronic damage to multiple organ systems, and an increased risk of readmission due to reinfection and other complications. Since …

… and transmission of superbugs. The Key Role of Endothelial Cells as Gatekeepers of Our Immune System in Heart and Vascular Diseases: Dr J. (Jeffrey) Kroon, Stichting Amsterdam UMC …

… and their modes of action, and on obtaining insight into, amongst other things, the microbiome, immunity, predictive parameters and individualised treatment. The focus area has four themes: Treatment Diagnostics of infection Risk analysis and prognostics Virus, immunity, immune response and pathogenesis Focus area 2: Care and prevention The emphasis within … current pandemic, and the safeguarding of these improved approaches and processes in the care system of the future. Various types of research are possible: evaluation pathways, action …

… T cell behavior towards effective killing of brain cancer T cells, fighter cells of the immune system, can be engineered to recognize and destroy tumor cells. Their dynamic nature is crucial …

… result in improved personalized patient management from which patiens will directly benefit. Immune tolerance of valve transplants: Translating prenatal protection mechanisms from womb to … grow and can elicit immune rejection. A perfect example of tissue that is not rejected by the immune system is a baby in it’s mother’s womb, even though the baby is for 50% made up of the father's …

… A.M. van der Does PhD Leiden University Medical Centre Lees meer over dit project Human Mucosal Immune System Model Guiding Treatment Choices in COVID-19 Project number: 10430132230003 Prof. …

… to the development of a better, personalized approach to SVD. A Chemical Approach for Immune Inhibitory Receptor Agonists Prof. L. Meyaard, UMC Utrecht, Prof. S.I. van Kasteren, … how drugs can be safely delivered to the cochlea. We will also develop animal free model systems to accelerate research into novel treatments for hearing loss. Resolving Endo-Lysosomal … growth. Understanding these cellular and molecular interactions responsible for weakening the immune system is crucial for improving diagnostics and therapies. One key, yet underexplored, …

… shows that MNPs from our environment can end up in the human body and could possibly affect our immune system, for example. Goal The current project, MOMENTUM, builds on these recent findings … brain, and placenta. Furthermore, the novel research on unravelling the effects of MNPs on our immune system will be continued, which will include research on pathogens, like bacteria and …

… research. The researchers will investigate themes that include premature birth, stimulating the immune system, diabetes and lung recovery following an inflammation. What is a Clinical …