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- This project investigated which of the many genetic mutations in the SORL1 have a risk-increasing or even causative effect on Alzheimer Disease.
- PMI-AD stratifies early-stage AD patients employing a novel mechnistic pathway-to-therapeutic algorithm resulting in cost-effective diagnostics and therapeutics
- The project establishes cognitive, imaging and fluid biomarker measures that allow i) stratification of individual presymptomatic carriers into a stage near to symptom onset, and ii) measurement of disease progression during that period.
- Veel neurologische aandoeningen vertonen afwijkingen in de witte stof, waaronder multiple sclerose, schizofrenie en de ziekte van Huntington. Witte stof wordt gekenmerkt door myeline. Echter dragen vele cellulaire structuren bij aan de ontwikkeling en instandhouding van een gezonde witte stof. Terwijl veel onderzoek in proefdieren wordt gedaan, representeren deze niet de witte stof in de humane…
- Policies to address physical inactivity, unhealthy diets and sedentary behaviour can affect the health and well-being of many people. However, it was unknown what policy measures had been implemented in Europe, what their effect is on lifestyle behaviours, and what the consequences are for socio-economic health inequalities. Also, there had not yet been a systematic study of how policy…
- Learn more about intraprofessional education and collaboration: power dynamics between physicians of different specialties (such as medical and family physicians).
- Lees hoe het PARCA-project antibioticavoorschrijfgedrag in kaart bracht en interventies ontwikkelde om het onjuist voorschrijven van antibiotica te verminderen.
- Persistent somatic symptoms (PSS) are common. Symptoms can persist for years and affect daily life. Read more about the long-term course of PSS.
- Reducing unnecessary antibiotic use for urinary tract infections in nursing home residents: educational materials to physicians and nursing staff
- Learn how GP’s can safely and efficiently exclude a diagnosis of pulmonary embolism in suspected patients when using the YEARS criteria
- Supervision of excellent medical residents: read how supervisors can improve the support and development of talented residents.
- Urgent action is required to stem the spread of antimicrobial resistance (AMR). However, because the pace of novel drug development lags behind the evolution of novel AMR determinants, new strategies of containment are required.MethodIn this multinational project proposal, researchers have worked on a resistance-reversal strategy based on the concept of collateral sensitivity (CS). CS between a…