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… 24 months Using the cell’s waste disposal system to remove cancer proteins Small mistakes in DNA can cause a cell to make proteins that turn the cell into a cancer cell. The researcher is … -
The emergence of antibiotic resistance is increasingly limiting treatment of bacterial infections. Bacteria can become...
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… MC The risk to develop a mental disorder such as autism or schizophrenia is determined by your DNA. The researchers apply a new method towards reading in the DNA whether somebody is susceptible and to better understand what goes wrong in the brain … -
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… particles with nanoparticles. It is known that these can lead to inflammatory responses and DNA damage. In addition, it seems likely that the smaller microplastics, which we are exposed to … -
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… time of infection, as well as six weeks later, measuring inflammation markers, immune cells, DNA profiles and protein levels. These values will give us an insight into the behaviour of the … -
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… established. It is hypothesized that this can be partially explained by variants in regulatory DNA-elements that control the activity of genes. Because of a lack of understanding, regulatory DNA-variants are currently being excluded from standard genetic analyses. This project aims to … and experimental tools will be employed with the goal of increasing knowledge about regulatory DNA-variants and to improve the diagnostic yield for inherited sensory disorders. Getting … -
… We will perform Whole Exome Sequencing (WES) using Next Generation Sequencing (NGS) on DNA from blood or saliva. In this workpackage we have two objectives: WP1.1. To diagnose …
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Afbeelding
… observed heterogeneity can be explained by the instability of the repetitive sequence in the DNA that is causing the disease. To investigate this, we will study and expand an existing … G. Huls, University Medical Center Groningen Cancer results from the gradual accumulation of DNA mutations in healthy cells. These mutations can lead to a growth advantage of the mutated …