Achtergrond afbeelding Achtergrond afbeelding darkmode

Zoeken op ZonMw

Zoeken op de website

Filters

5 resultaten gevonden voor 'Tuberculosis'.

  • New intervention strategy for tuberculosis: blocking multiple essential targets

    Looptijd:
    04/2015
    -
    11/2018
    Project descriptionMycobacterium tuberculosis is the causative agent of tuberculosis (TB), a disease responsible for almost 1.5 million deaths per year. In recent years, different classes of drug resistant strains have emerged, making the discovery of novel tuberculostatic drugs a major priority. A major disadvantage of most existing and new TB compounds is that they target a single molecule…

  • Team science for groundbreaking fundamental research receives boost of 12.5 million euros

    Nieuws
    10 juni 2021
    Sixteen research teams will set up innovative collaborations that contribute to innovation in science and healthcare for the longer term. Each team has received a maximum of 750,000 euros from the programme ZonMw Open Competition. The research groups will investigate, for example, the genetic factors of heart muscle diseases, better treatment of damage to the retina and the development of…

  • ZonMw joins GLoPID-R for infectious diseases

    Nieuws
    19 april 2019
    GloPID-R is pleased to welcome the Netherlands Organisation for Health Research and Development (ZonMw), represented by Suzanne Verver, into the network. GloPID-R is a unique international network of major research funding organizations. The network of 27 countries facilitates a rapid and effective research response to infectious disease outbreaks.

  • Bacterial histidine kinase inhibitors as novel antibacterials with low potential for resistance development

    Looptijd:
    04/2017
    -
    12/2023
    Infections caused by bacteria resistant to most antibiotics (so-called multidrug resistant bacteria) remain a global problem. The lack of new antibiotics is a major social problem and threat to human and animal health.AimIn this antimicrobial discovery project, researchers focused on developing novel antibiotics for the highly virulent and antibiotic-resistant human pathogens (called the ESKAPE…

  • Non-conventional approaches for peptidoglycan cross-linking inhibition

    Looptijd:
    03/2015
    -
    04/2019
    Bacteria can become resistant against beta-lactam antibiotics (Penicillin) by replacing their 3-4 peptide crosslinks by 3-3 crosslinks in the peptidoglycan layer in their cell wall that gives the bacterium its shape and protects it against mechanical stress. Peptidolglycan consists of a network of sugars strands that are interconnected by peptide crossbridges. Hardly anything was known about the…