Biocide Impact on Antimicrobial Resistance in Enterobacterales in One Health settings

BIORESIST

Due to the imprudent use of antimicrobials in livestock, antimicrobial resistance is now prevalent in various domains. Between these domains, antimicrobial resistance can be transmitted. One of the most successful interventions against antimicrobial resistance has been reducing the use of antibiotics to lower selection pressure.

To reduce the risk of disease spread while maintaining the feasibility of intensive farming, biocides are now more widely used for disinfection. Resistance mechanisms against biocides can lead to the selection and spread of antimicrobial resistance.

Aim

Researchers will determine if the use of biocides has a selective effect on antimicrobial resistance. They will also look at whether biocides cause more risk of co-selection of antimicrobial resistance than other agents.

Method

Data and bacterial collections from various European reference laboratories for antimicrobial resistance will be compared to determine whether the use of biocides can lead to the co-selection of antimicrobial resistance. Based on focus groups, the use of biocides will be compared between different countries.