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- Alzheimer's disease is the most common form of dementia. It is expected that 1 in 5 people in the Netherlands will develop dementia in the future, but there are still no effective treatments. Researchers aim to develop such treatments. Multiple processes are involved in Alzheimer's disease, such as the clustering of amyloid and tau proteins, as well as inflammatory reactions in the brain…
- In dit project worden processen om te identificeren die gemeenschappelijk zijn voor zowel veroudering als Alzheimer en die vervolgeffecten hebben op cognitieve achteruitgang onderzocht.
- Lees meer over het project dat behandeling en diagnose wil verbeteren voor de ziekte van Creutzfeldt-Jakob.
- Neurodegeneratieve ziekten kunnen ontstaan door ophoping van alfa-synucleïne. Dit project onderzoekt de effecten van dit eiwit.
- In dit project wordt onderzocht of S14 en andere vetten de schakel vormen tussen ons Westers eetpatroon, overgewicht en het ontstaan van dementie.
- Vancomycin-resistant Enterococcus faecium (VRE) is a multi-resistant bacterium, capable of causing outbreaks in hospitals. This project aims to determine the best VRE screening protocol.
- Cryptosporidium is a unicellular parasite that can cause intestinal inflammation and diarrhea in humans and animals. New typing methods will be applied to gain insight into the types of Cryptosporidium.
- Maternal vaccination effectively protects infants against infectious diseases directly after birth, this study compares transplacental antibody transfer after maternal vaccination
- Detection of a urinary tract infection (UTI), such as cystitis or pyelonephritis, in older people is challenging, this study aims to validate the performance of biomarkers in daily practice.
- Invasive and chronic pulmonary aspergillosis (PA) are severe and potentially fatal fungal infections, this project investigates a method to create a reliable monitoring system.
- Bacteriophages and plasmids are often specific to a particular source, this project will investigate how CRISPR dynamics are related to environmental niche adaptation and recalibrate source attribution models.
- This pilot project investigates the risk of re-infection in sepsis survivors in the first year after hospital discharge and estimate the adverse outcomes attributable to its occurrence.