Understanding the antibiotic transport channels of Mycobacterium tuberculosis: peeping through the wall
De tuberculose bacterie is opmerkelijk resistent tegen antibiotica vanwege zijn versterkte celwand. Wij gaan ontrafelen hoe deze celwand werkt om de verdediging in stand te houden en tegelijkertijd essentiële voedingsstoffen te transporteren. Deze kennis gaan we gebruiken om nieuwe antibiotica te ontwikkelen.
Producten
Titel: Modulating mycobacterial envelope integrity for antibiotic synergy with benzothiazoles
Auteur: Habjan E, Lepioshkin A, Charitou V, Egorova A, Kazakova E, Ho VQ, Bitter W, Makarov V, Speer A.
Magazine: Life Sci Alliance
Link: https://www.life-science-alliance.org/content/7/7/e202302509
Auteur: Habjan E, Lepioshkin A, Charitou V, Egorova A, Kazakova E, Ho VQ, Bitter W, Makarov V, Speer A.
Magazine: Life Sci Alliance
Link: https://www.life-science-alliance.org/content/7/7/e202302509
Titel: PPE51 modulates membrane integrity in Mycobacterium marinum.
Auteur: Charitou V, Izquierdo Lafuente B, Habjan E, Kuijl C, Willemse JJ, Bitter W, Speer A.
Magazine: mBio
Link: https://journals.asm.org/doi/10.1128/mbio.01044-25?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Auteur: Charitou V, Izquierdo Lafuente B, Habjan E, Kuijl C, Willemse JJ, Bitter W, Speer A.
Magazine: mBio
Link: https://journals.asm.org/doi/10.1128/mbio.01044-25?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Titel: A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis
Auteur: Lissner R, Franklin A, Benedict ST, Charitou V, Speer A, Knol J, Jimenez C, Moynihan PJ, Nejentsev S, Kuijl C, Bitter W.
Magazine: mBio
Link: https://journals.asm.org/doi/10.1128/mbio.02119-25?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Auteur: Lissner R, Franklin A, Benedict ST, Charitou V, Speer A, Knol J, Jimenez C, Moynihan PJ, Nejentsev S, Kuijl C, Bitter W.
Magazine: mBio
Link: https://journals.asm.org/doi/10.1128/mbio.02119-25?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed