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  • Living Well

    Duration:
    06/2017
    -
    02/2021
    Living Well: avatar Anne voor mensen met dementie Door vergeetachtigheid, als gevolg van ouderdom, niet-aangeboren hersenletsel of dementie, verliezen mensen soms de controle over hun eigen leven. Daardoor raken ze de aansluiting bij de wereld om hen heen kwijt, en soms zelfs hun waardigheid. Anne, een virtuele assistent, kan uitkomst bieden voor deze groep. Hoe het werkt Voor mensen die…
  • AWARE-WWTP

    Duration:
    06/2017
    -
    12/2021
    Read how is investigated wastewater treatment plant employees and local residents are more likely to carry antibiotic-resistant bacteria.
  • Hospital-acquired infections, including Multidrug-resistant Enterobacteriaceae (MDR-E), are recognised to be an important public health issue and cause significant burden on health care systems worldwide. While classic infection control strategies mainly target the spread of these pathogens at intra-hospital level (inside a hospital), inter-hospital (between various hospitals and health care…
  • Read how this project gained more insight into the resistance mechanisms of pneumococci, particularly the environmental, immunological and pharmacological factors.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is characterised by clonal spread. MRSA clones are unequally distributed across the world and different clones are dominant at different times. AimThe MACOTRA project studied the interaction between MRSA, humans and the environment. The researchers used mathematical models to gain a better understanding of MRSA dynamics.ResultsA main predictor of…
  • The rapid spread of multidrug resistant bacteria threatens the treatment of even simple infections in the near future. However, little is known about how bacteria develop resistance on surfaces.AimThe aim of this project was to investigate fundamental mechanisms that shape antimicrobial resistance in biofilms in relation to the surface and then translate those findings into clinical practice…
  • Infections caused by bacteria resistant to most antibiotics (so-called multidrug resistant bacteria) remain a global problem. The lack of new antibiotics is a major social problem and threat to human and animal health.AimIn this antimicrobial discovery project, researchers focused on developing novel antibiotics for the highly virulent and antibiotic-resistant human pathogens (called the ESKAPE…
  • Infections with antibiotic resistant bacteria, for example an urinary tract infections, are difficult to treat. Because of this, antibiotic resistance is an important public health threat. In Europe, the ESBL-producing gut bacteria (ESBL-G), are the most important cause of such infections, with around 400.000 cases per year. 5% of the Dutch inhabitants carries ESBL-G, while outside the Netherlands…
  • Bacteria are increasingly becoming resistant to antibiotics. This is an immediate threat to health care in the Netherlands and elsewhere. Recent studies show that, in Europe alone, more than 30.000 individuals die every year due to an infection with an antibiotic-resistant bacterium.AimThis project studied the pathways by which resistant bacteria can emerge in complex ecosystems, in which they can…
  • Training of physical fitness is an important component of orthopedic geriatric rehabilitation. Read more about the recommendations from Fit4Frail.
  • Combinatorials

    Duration:
    03/2016
    -
    03/2019
    Infections with antibiotic-resistant bacteria are a major threat to public health. Due to globalisation and poor use of antibiotics, resistance is spreading rapidly. Moreover, few new antibiotics have come onto the market in the last 20 years.AimIn this international project, researchers have been using the latest high-throughput screens to look for new combinations of drugs that can effectively…
  • Respiratory tract infections are common and are increasingly caused by bacteria that are no longer sensitive to commonly used antibiotics.ObjectiveThis project aimed to expand the therapeutic arsenal against respiratory tract infections by testing agents that stimulate the immune system.ResultsThe AMC had 2 specific tasks. First, a culture system of human respiratory epithelial cells was set up…