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resultaten gevonden voor 'Resistance'.
- Read how the SHIELD-project strengthens natural defences through ‘trained immunity’, enabling the immune system to combat fungal infections more effectively.
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It is still unclear exactly how lifestyle factors, including diet, affect our health and the development of diseases. Why do some people contract a particular condition, whilst others do not? The environment we live in certainly plays an important role here, but genetic characteristics are also key. Healthy Diet for a Healthy Life (HDHL) is funding research projects aimed at preventing diet… - Researchers will determine the effectiveness of antibiotic stewardship programs in the intensive care unit and formulate recommendations for implementation.
- Read how researchers will use genome sequencing to study the fungal genus Candida in hospitals to limit its transmission.
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In a growing number of calls for grant applications, ZonMw allows the production of FAIR (meta)data in projects. This page provides information about ZonMw's approach for this. That is followed by instructions for what grant applicants and recipients must do to get started with FAIR (meta)data. - Project descriptionMycobacterium tuberculosis is the causative agent of tuberculosis (TB), a disease responsible for almost 1.5 million deaths per year. In recent years, different classes of drug resistant strains have emerged, making the discovery of novel tuberculostatic drugs a major priority. A major disadvantage of most existing and new TB compounds is that they target a single molecule…
- Bacteria can become resistant against beta-lactam antibiotics (Penicillin) by replacing their 3-4 peptide crosslinks by 3-3 crosslinks in the peptidoglycan layer in their cell wall that gives the bacterium its shape and protects it against mechanical stress. Peptidolglycan consists of a network of sugars strands that are interconnected by peptide crossbridges. Hardly anything was known about the…
- Resistance against β-lactam antibiotics is a serious health issue. Often it is caused by bacteria producing enzymes capable of inactivating these antibiotics, β-lactamases. This can be prevented by combining the antibiotic with a compound able to inhibit the bacterial enzyme. AimThe aim of this project was to find new β-lactamase inhibitors. To achieve this a large botanical extract library was…
- Read more about the treatment of urinary tract infections (UTIs) without signs of tissue invasion (afebrile UTI (a-UTI)) in men in general practice
- This project develops an accurate screening and surveillance of yeasts to be prepared for the emergence of Candida auris.
- In this controlled study the acceptability, utility and feasibility of self-swabbing instead of physician-swabbing will be evaluated.
- Vancomycin-resistant Enterococcus faecium (VRE) is a multi-resistant bacterium, capable of causing outbreaks in hospitals. This project aims to determine the best VRE screening protocol.